• Users Online: 106
  • Print this page
  • Email this page
Year : 2012  |  Volume : 1  |  Issue : 1  |  Page : 42-46

Noninvasive respiratory support in the preterm neonate with hyaline membrane disease: Bubble CPAP vs Conventional CPAP - A randomised controlled trial

1 Assistant Professor, Department of Respiratory Therapy, Manipal College of Allied Health Sciences, Manipal, India
2 Professor of Paediatrics and Head, Neonatal Intensive Care Unit, Kasturba Medical College, Manipal, India

Correspondence Address:
Eribaweimon Shilla
Assistant Professor, Department of Respiratory Therapy, Manipal College of Allied Health Sciences, Manipal
Login to access the Email id

Source of Support: None, Conflict of Interest: None

Rights and PermissionsRights and Permissions

Background: Continuous Positive Airway Pressure (CPAP) is a noninvasive, gentle method of providing respiratory support to spontaneously breathing neonates. Objective: To compare the effectiveness of bubble CPAP (B-CPAP) over conventional CPAP (C-CPAP) in view of improvement in the severity of respiratory distress in preterm neonates with hyaline membrane disease (HMD). Methods: The targeted populations were all preterm and late preterm neonates admitted in neonatal intensive care unit (NICU) with HMD and respiratory distress, requiring noninvasive ventilation. Neonates who met the inclusion criteria were randomly allocated to either B-CPAP or C-CPAP using random table method. CPAP was started at the earliest signs of respiratory distress and postextubation. Result: Respiratory distress was assessed before and after initiation of CPAP based on Downe's score. The decrease in Downes score was statistically significant in the B-CPAP group compared to C-CPAP group. Primary CPAP failure was 23% (7/30) in the B-CPAP group compared to 10% in the C-CPAP group (3/30) (p = 0.16). The number of days on CPAP, oxygen therapy and NICU stay showed no significant difference. Complications of CPAP were not significantly different. Conclusions: B-CPAP is as effective as C-CPAP in improving respiratory distress. However, CPAP failure rates are higher in B-CPAP group with preterm of extreme low birth weight babies (<1000 g). B-CPAP is one of the most effective and economical mode of noninvasive respiratory support for preterm neonates with HMD.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded157    
    Comments [Add]    

Recommend this journal